Chile stretches like a silk ribbon between Pacific swells and glittering Andean peaks, and a luxury trip here can feel like curating your own private universe. Begin in Santiago at the Ritz-Carlton or Singular Lastarria, where rooftop pools mirror the snow-dusted Cordillera at sunset. Explore the historic Centro and artsy Bellas Artes, then ride the cable car to Cerro San Cristóbal for a champagne toast above the city’s lights. Fly north to San Pedro de Atacama, checking into Nayara Alto Atacama or Tierra Atacama, where earth-toned suites blend into copper cliffs. Private guides lead you at dawn to El Tatio Geysers and at dusk to Moon Valley, while astronomers unveil the Milky Way through powerful telescopes in some of the world’s clearest skies. Continue to the Colchagua Valley and Millahue, staying at Vik Chile or Clos Apalta Residence. Sip carmenère among sculpture-dotted vineyards, then drift over patchwork fields in a sunrise hot-air balloon. Farther south, Patagonia awaits. At Torres del Paine, book Explora Patagonia or Awasi for tailored treks to the base of the granite towers, condor-spotting rides on horseback, and glacier cruises on Lake Grey with whisky served over ancient blue ice. Conclude with a coastal interlude in Valparaíso at Casa Higueras, its infinity pool hanging above colorful hillside murals and the restless sea, before your final, languid meal of king crab and Chilean Sauvignon Blanc.